ObjectivePatients with breast cancer carrying BRCA1 and BRCA2 genetic alterations show poor prognoses.However, the efficacy of pharmacotherapies for patients with advanced breast cancer Mesh Cap carrying BRCA1/2 pathogenic variants remains unclear.This study aimed to conduct a network meta-analysis to assess the efficacy and safety of various pharm
Mitigating Risk of Failure by Expanding Family Entrepreneurship and Learning from International Franchising Experiences of Johnny Rockets: A Case Study in Pakistan
It is generally believed worldwide and backed by research too that startups face a high risk of failure and eight to nine out of ten ideas may not work (Hisrich, Peters, & Shepherd, 2009).However, many experts claim that the situation can turn vice versa for family entrepreneurship (or creative family businesses) and franchise ventures (Francorp, 2
Comparison of Functional Recovery in the Very Early Period After Surgery Between Plate and Nail Fixation for Correction of Stable Femoral Intertrochanteric Fractures
GAMMA E COMPLEX Purpose: This study aimed to compare the differences in functional recovery between patients undergoing plate and nail fixation in the very early period after surgery.Method: This study was designed as a controlled clinical trial that included 18 patients who were surgically treated with either dynamic hip screw as plate fixation or
Analysis of the System with Vacations under Poissonian Input Stream and Constant Service Times
In the paper approximate formulas for the mean waiting times and the buffer dimensioning in the Mesh Cap system with vacations fed by the stream of Poissonian type with constant service times is shown.Furthermore, in the considered system the time intervals of the availability/notavailability of the service are constant and are run alternately acco
Hyper-parameter tuned deep learning approach for effective human monkeypox disease detection
Abstract Human monkeypox is a very unusual virus that can devastate society.Early identification and diagnosis are essential to treat and manage an illness effectively.Human monkeypox disease detection using deep learning models has attracted increasing attention recently.The virus that causes monkeypox may be passed to people, making it a zoonotic